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30 January 2026
Vessel Vulnerability
Cerebral small vessel disease (CVD) is a leading cause of stroke and dementia but, as human brain vessels aren’t accessible for research, it's hard to study directly. Here, a zebrafish model of CVD reveals the role of mutations in the gene foxf2. Fish with mutated foxf2 have abnormal pericytes, the cells that wrap around vessels and are key to vascular formation and stability
Read the published research article here
Written by
- Image from work by Merry Faye E Graff and colleagues
- Alberta Children’s Hospital Research Institute, University of Calgary, Calgary, Canada, Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Canada
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in eLife (Reviewed Preprint), January 2026
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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