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Spinal Cord-anoids

28 January 2026

Spinal Cord-anoids

Organoids – mini organs or tissues grown in the lab from relevant cells or stem cells – are powerful models for dissecting the characteristics, genetics and interactions that make up the real-life setting, commonly far too big and developed to track in real time or consider as a whole. Here, human pluripotent stem cells have been manipulated to grow as an organoid to mimic the early spinal cord and a key role revealed for a protein called YAP in shaping the cord's inner space or lumen (part of the cord's natural developmental process)

Read the published research article here

Written by Lindsey Goff

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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