Focussing on cells in the lining (epithelial cells) of mouse intestine just as they begin to become cancerous has revealed how they're equipped to continue on their fateful path. Stress signals displayed by these early tumour cells triggers the cell bed – fibroblasts – on which they rest to sculpt a nutritious niche perfect for the cancer to thrive, and which is even sufficient to make normal epithelial cells become tumours
Read the published research article here
Image made using Leica Microsystems microscopy
Written by
BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.