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23 September 2026
Long Distance Information
DNA isn't end-to-end genes encoding proteins – in between the gene codes are non-coding regulatory elements , including some that play vital roles in when genes are 'read-off'. But identifying their unique codes among the permutations of 'ATGC' (letters representing the four DNA nucleotide bases) is a challenge because they may be sited quite a distance from the gene on which they act. Using a shrimp-like crustacean Parhyale hawaiensis as a model with a genome of similar size to ours, here researchers have developed a method combining bulk with single-nucleus sequencing to identify such cis-regulatory elements genome-wide
Read the published research article here
Written by
- Image from work by Gillian Forbes, Emilia Skafida and Irene Karapidaki, and colleagues
- Institut de Génomique Fonctionnelle de Lyon (IGFL), École Normale Supérieure de Lyon, CNRS and UCBL Lyon 1, Lyon, France, Centre National de la Recherche Scientifique (CNRS), Paris, France
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in eLife (reviewed preprint), September 2026
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