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15 September 2026
Ultra Reconstruction
With cryo-electron microscopy (cryo-EM) researchers can peer right into the ultrastructure of a cell or organism, allowing them to observe tiny structures in their natural setting at high resolution. Here, the view has been improved by an approach called MOSAIC that streamlines the making of a large montage of cryo-EM images (tomograms) taken at different angles in conjunction with software called MontageMaker for computationally 'stitching' them together. The video shows such treatment of an entire yeast cell with segmentation highlighting each of the cell's inner structures
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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