Into the Deepbone

Human bone marrow mesenchymal stem cells (HMSC) can differentiate into any of the many bone marrow-derived cells (except the red and white blood cells) and are of great interest to researchers in many biomedical fields, including tissue regeneration, cancer and stem cell therapies. Now, thanks to a new bone tissue clearing approach called DeepBone, they can be studied and mapped in 3D within their natural bone marrow environment (components of which can also be characterised) – this study compares HMSC in the marrow of the young and aged

Read the published research article here

Written by Lindsey Goff

Lindsey Goff

Editor-in-Chief

Formerly immunologist for Cancer Research UK, Lindsey has since moved into the field of scientific publishing. She looks after all BPoD editorial matters.

• Video from work by Nelson Tsz Long Chu and colleagues
• Centre for Bone and Arthritis Research, Institute of Medicine at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
• Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
• Published in Nature Biomedical Engineering, April 2026