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16 August 2025

Pumped Up

Using an array of techniques including live imaging and computational modelling, this study reveals the shaping of the functional architecture of the zebrafish heart during development. After initial tissue stretching as cardiac contractile forces increase, a drop in tissue tension regulated by the Notch molecular pathway follows and, in response to cardiac forces and stretch, stable growth of the organ to full capacity ensues

Read the published research article here

Written by Lindsey Goff

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What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.