04 July 2025
Heart-tuning Channel
A molecule in the cells of developing of heart vessels called PIEZO2 responds to mechanical cues (pressure of blood and heart beat) is key to a critical phase of coronary vasculature remodelling. Loss of PIEZO2, part of a so-called ion channel, leads to vessels (highlighted in these pre-birth mice hearts in blue) misshaped and mis-branching (lower eight panels), and heart enlargement
Read the published research article here
Written by
- Image from work by Mireia Pampols-Perez and colleagues
- Molecular Pathways in Cortical Development, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Nature Cardiovascular Research, June 2025
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