17 April 2025
Key to Evasion
This study identifies a protein called MGAT1 as underlying triple-negative breast cancer cells' ability to avoid immune recognition. MGAT1 causes an increase in another protein, CD73 (seen here in green), on the membrane of the cancer cells which dampens attack by the immune system's CD8+ T-cells
Read the published research article here
Written by
- Image from work by Junlong Jack Chi, Ping Xie and Mary Hongying Cheng, and colleagues
- Laufer Center for Physical & Quantitative Biology, Stony Brook University, Stony Brook, NY; University Feinberg School of Medicine, Chicago, IL; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Nature Communications, April 2025
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