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10 June 2025
Nuclear Leukaemia
The most common genetic fault found associated with the blood cancer acute myeloid leukaemia is a nucleophosmin gene NPM1 mutation. Normal NPM1 activity maintains structures of the cell nucleus called nucleoli, but in NPM1-mutated AML nucleoli are distorted and malfunction, faults which are potential therapeutic targets
Read the published research article here
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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