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11 September 2026
Do Callus
Bone can heal itself up to a point – successful repair involves formation of a cartilaginous transient tissue, the 'fracture callus' which develops a blood supply, mineralises, and becomes mature bone. But if the gap's too big, knitting the wound is a bridge too far. Here, by culturing bone membrane-derived progenitor cells plus blood vessel lining cells researchers have developed 'callus organoids' which when implanted at a bone defect site orchestrate bone regeneration by the natural process
Read the published research article here
Written by
- Still from a video from work by Hanna Svitina and colleagues
- Skeletal Biology & Engineering Research Centre, Department of Development & Regeneration, KU Leuven, Leuven, Belgium
- Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Cell Stem Cell, September 2026
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