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10 July 2025
Actin Excited
A cell's inner scaffolding or cytoskeleton of actin shapes their movements and is controlled by enzyme activity, but exactly how has been unclear. Here, complicated feedback mechanisms involving p21-activated kinase enzymes are revealed to underlie the excitability of the actin scaffold. In the video dramatic disruption of the cytoskeleton is seen when the p21-activated kinase inhibitor G5555 is added to the cell
Read the published research article here
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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