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Taking Sides

18 June 2025

Taking Sides

Getting organs on the correct side of our body's left-right axis, along with heart and kidney development is regulated in part by molecules in the Wnt signalling pathway (a series of different Wnt proteins passing signals within cells). This study using Xenopus frog embyros, examines a gene variant found in a child with mirror image organ placement and other developmental defects, revealing the key role of Wnt11. The image shows a fluorescently-labeled two-headed frog embryo

Read the published research article here

Written by Lindsey Goff

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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