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13 May 2025

Calm in ER

Within a cell there's a world full of organelles (the cell's 'organs' each with a specialised role) and protein scaffolding (the cytoskeleton which includes actin, that shapes the cell and organises to move it). This study of proteins located around (spatial proteomics) the endoplasmic reticulum (ER shown in blue; the organelle key to protein production and transporting them to the right place) reveals that a protein called calmin (in green) tethers the ER with actin (in magenta) to co-ordinate cell adhesion to the substrate, regulating migration

Read the published research article here

Written by Lindsey Goff

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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