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Mapping how nerve fibres are organised in the brain's white matter

10 May 2025

Monkey Matter

The brain uses a complex network of bundles of nerve cells – neurons – to transfer information as we interpret and respond to the world around us. Many of its details are still a mystery, leaving scientists searching for new angles on this vital living supercomputer. Here, researchers examine a monkey’s brain using x-rays at the European synchrotron. Particles forced to loop in circles at high speeds are fired at the tissue sample, uncovering new details based on how the particles scatter. The experiments reveal nerve cell projections known as axons (highlighted as thin multi-coloured lines) and blood vessels (orange) inside a complex region of the cerebral cortex of a monkey. Interestingly, researchers find some groups of axons form layers or laminar structures, adding to our picture of the human brain’s similar connectome.

Written by John Ankers

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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