29 April 2025
A Model Ending
A mouse model of the consequences of telomere (regions at the end of chromosomes) shortening associated with ageing and cancer development: this study uses CRISPR editing to knock out TEN1, one of the components of the telomere maintenance complex of proteins, creating a model of the inherited disease dyskeratosis congenita
Read the published research article here
Image created using Leica Microsystems microscopy
Written by
- Image from work by Adrián Sanz-Moreno, Lore Becker and Kan Xie, and colleagues
- Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg; Translational Biogerontology Lab, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Science Advances, April 2025
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