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20 November 2024
Junction Dysfunction
Lafora disease is a fatal neurodegenerative genetic disorder associated with cognitive decline, ataxia and seizures. Using a mouse model mimicking human genetic faults found in Lafora disease this study, instead of focussing on brain aspects covered by other research, finds abnormalities in neuromuscular junctions (the interface via which nerves tell muscles what to do) revealing the importance of the Lafora-implicated gene activity therein
Read the published research article here
Written by
- Image from work by Monica Shukla, Deepti Chugh and Subramaniam Ganesh
- Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in and on the cover of Disease Models & Mechanisms, October 2024
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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