20 November 2024
Junction Dysfunction
Lafora disease is a fatal neurodegenerative genetic disorder associated with cognitive decline, ataxia and seizures. Using a mouse model mimicking human genetic faults found in Lafora disease this study, instead of focussing on brain aspects covered by other research, finds abnormalities in neuromuscular junctions (the interface via which nerves tell muscles what to do) revealing the importance of the Lafora-implicated gene activity therein
Read the published research article here
Written by
- Image from work by Monica Shukla, Deepti Chugh and Subramaniam Ganesh
- Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in and on the cover of Disease Models & Mechanisms, October 2024
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