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Science Synergy
10 June 2015

Science Synergy

A not-for-profit organisation known as the Structural Genomics Consortium (SGC) was formed in 2003 with the premise that drug discovery research should be open access, allowing researchers to work together sharing insight and expertise. By making all their research freely available to the scientific community, the SGC has already aided and accelerated drug discovery. Since its launch, the SGC has characterised more than 1700 high-resolution crystal structures of human and parasite proteins – pictured are ribbon diagrams of four of many medically relevant human proteins publicly released by the SGC. Today they’re exploring a new avenue of research by developing assays for human-derived cells. Donated tumour cells and stem cells from patients with cancer or neurological diseases such as Parkinson’s, will be analysed to determine their function and activity. These cells will then serve as targets for new medicines, and can be tested against the SGC’s current catalogue of chemical probes.

Written by Helen Thomas

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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