Vision begins at the eye's retina – activated by light, electrical signals from the retina travel along neurons via the optic nerve to the brain where they're processed into 'sight'. As this system develops, the neurons don't land randomly in the brain, they follow a closely-regulated pattern reflecting the point of origin in the retina – mapping to the brain in a process called retinotopy. Here, in fruit flies researchers uncover the fine details, involving molecular gradients and adhesive forces, that control the preservation of the eye pattern as the neurons' projections (axons) establish in the brain
Image made using Leica Microsystems microscopy
Read the published research article here
Written by
BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.