31 May 2025
Tau Bags
Brains of patients with Alzheimer's disease (AD) bear characteristic clusters of tau protein within neurons. This study finds truncated tau filaments (shown in magenta) within and that are tethered to the membrane (yellow) of extracellular vesicles (lipid-wrapped sacs associated with cells throughout the body whose function is delivering or clearing molecules) from AD patient brains providing insights into tau's behaviour and ways to target it therapeutically
Read the published research article here
Written by
- Image from work by Stephanie L. Fowler and Tiana S. Behr, and colleagues
- UK Dementia Research Institute at University College London, London; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
- Published in Nature Neuroscience, November 2024
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