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Connect the Dots

27 December 2025

Connect the Dots

Without looking, is there a small freckle on the back of your hand? Are you sure? Small, innocuous flourishes on the skin are easy to miss, and hard to keep track of. But accurately assessing skin marks is important to dermatologists, and a new computer vision technology could reduce reliance on subjective visual assessments. The approach identifies target regions of skin, generates an energy map that makes freckles stand out, enhances contrast and then segments (partitions the images into regions) freckles. Compared to standard colour-based segmentation (left), the technology showed improved accuracy (right, with greater overlap (green) between the model’s predictions (red) and the actual freckle pattern (blue)). Software that can identify details as subtle as freckles could improve non-invasive assessment for automated screening of skin diseases, monitoring skin changes over time, or even be applied to identifying important subtle differences in contrast between other types of tissue, such as when analysing wound healing.

Written by Anthony Lewis

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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