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15 December 2025
Tumours and Seizures
Seizures – a sudden excessive brain activity changing behaviour – are commonly triggered in patients with brain tumours, but why has been unclear. Here, looking at features, including synaptic activity (connecting to other neurons) and gene expression, of pyramidal neurons around brain tumours differences are found between patients with and without seizures. Using a mouse model, alterations in neurons called paroxysmal depolarizing shifts were identified as a potential biomarker for seizure risk
Read the published research article here
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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