10 June 2024
Piezo Ignites Macrophages
Analysing the relationship between macrophages – large, multifunctional cells of the immune system – and fibrosis of the liver resulting from repeated injury and repair in mice reveals the role of a molecule called Piezo1 via which macrophages sense mechanical signals of tissue 'stiffness', alerting them to clear dead cells limiting inflammation and fibrosis
Read the published research article here
Written by
- Image from work by Yang Wang, Jin Wang and Jiahao Zhang and colleagues
- Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Image originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)
- Published in Science Advances, June 2024
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