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Piezo Ignites Macrophages

10 June 2024

Piezo Ignites Macrophages

Analysing the relationship between macrophages – large, multifunctional cells of the immune system – and fibrosis of the liver resulting from repeated injury and repair in mice reveals the role of a molecule called Piezo1 via which macrophages sense mechanical signals of tissue 'stiffness', alerting them to clear dead cells limiting inflammation and fibrosis

Read the published research article here

Written by Lindsey Goff

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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