More experts are better than one for training bioimage interpretation algorithms
Making observations of life is the most fundamental discovery process of biology. Today’s imaging technology shows scientists more detail than ever before, with vast and complex image sets produced in labs around the world every day. Analysing these data takes specialist skills and lots of time, and is subject to the individual analyst’s subjective perspective. Automating the process would speed it up and remove inconsistencies. Machine algorithms must be trained by examples, however, so it’s possible that they might replicate the subjectivity they aim to eradicate if trained by one expert’s examples. To investigate, researchers compared algorithms trained on a single expert’s work to those trained on many experts’ analyses (pictured, with different experts’ marks on a mouse brain image in different colours). Training the algorithm with many people’s input reduced subjectivity and improved outcomes, showing that many teachers are better than one.
BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.