A picture’s worth a 1000 words but for the visual system, an image represents over 100 million puzzles to solve. This is the number of light-sensitive cells – called rods and cones (comb shapes in this drawing of the retinal cell layers) – that each sends a signal from the retina when we open our eyes. To avoid being overwhelmed, the visual system needs to extract the most important aspects of the scene from this deluge. Horizontal cells (in yellow), whose tentacles connect to multiple rods and cones, play this important role. They compare activity from groups of cells and then block all but the strongest signals from reaching the brain for processing. And they can even deal simultaneously with the different demands of spatial and temporal information. This ability that’s long-puzzled scientists now appears to involve an enzyme (shown by small green patches) that adapts nerve pathways to judge temporal cues.
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
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