As strong as steel with the ability to stop bullets, spider silk is incredible. Its combination of strength, flexibility and its benign effect on the human body makes it ideal for medicinal applications. Replacing damaged tendons, sewing up wounds and building scaffolds for new cells to grow upon are just a few potential uses. Difficulties associated with extracting spider silk, however, mean that if these dreams are to be realised at scale creating artificial mimics is essential. And for this, scientists need to decipher the mysterious process that underpins silk production. New evidence suggests that turning the basic material of long proteins into solid fibres may revolve around changes in acidity. In this silk-producing gland, the acidic concentration (higher acidity indicated by more intense yellow) peaks midway through the twisted duct before dropping off towards the tapered exit. A small but important step towards understanding this wonder material.
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.