Today’s 2013 camel wrestling championships in Selçuk, Turkey will see the humped quadrupeds face-off in a battle of strength and power. And they’re engaged in another fight too – against HIV, albeit indirectly. Deciphering how HIV goes about its destructive deeds would be made much easier if scientists could watch the process unfurl. Now, uniquely useful camelid antibodies have made this possible. By fusing antibodies that latch onto one element of the HIV-forming machinery with a green fluorescent protein, cells will be seen glowing – under a special microscope – wherever the virus is forming. This image, a composite of 120 thin slices through a cell, shows virus particles (green) assembling around the cell’s surface. With help from camels and their kin to visualise HIV’s activity in living cells researchers could be closer to striking the knockout blow against HIV/AIDS.
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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.