Sleeplessness is associated with accumulated DNA damage in neurons in sea anemones
Every animal possessing a nervous system – from anemones to zebras – requires some form of sleep. And this universality implies sleep’s critical function for maintaining healthy neurons. By studying the nervous systems of a variety of animals, including the sea anemone, which has a simple neural net (pictured) but no brain, scientists now know that wakefulness is associated with DNA damage accumulation in neurons and that sleep enables its repair. When sea anemones were forced to stay awake for longer than usual, their neurons accumulated more damage and they needed more recovery sleep. Of course, DNA damage can be problematic for any cell, but the fact that neurons are, largely speaking, non-dividing and irreplaceable might explain why repairs in these cells are particularly crucial. With all that in mind, if you happen to be reading this late at night, you know what to do, don’t you.
Written by
BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.